Designing Proteins for Health
Developed by Google DeepMind, AlphaProteo is a revolutionary AI system for designing novel, high-strength protein binders. Unlike AlphaFold which predicts structures, AlphaProteo creates completely new proteins that successfully bind to target molecules. This capability can dramatically accelerate drug discovery, disease understanding, and biological research, including successfully designing a binder for VEGF-A for the very first time.
Binding Affinity Breakthroughs
AlphaProteo achieves anywhere from 3 to 300 times better binding affinities than the best existing methods on tested targets, averaging at 10x improvement.
Target Binding Success
AlphaProteo demonstrates highly-competitive experimental success rates across diverse and complex target proteins, including those involved in cancer and inflammation.
How AlphaProteo Works
Trained on extensive data from the Protein Data Bank (PDB) and AlphaFold structures, AlphaProteo learns how molecules bind to generate custom candidate binders for targeted locations.